M/Z: 367.981
Hit 3 annotations: Phosalone_[M+H]+; methyl 5,7-dichloro-3,8-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylate_[M]+; cis-2,3-Dihydrodiol-DDE_[M+NH4]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 4 Reference Ions Near m/z 367.981
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000015486 Reliable | 367.9885 | 367.9883 ~ 367.9886 MzDiff: 0.9 ppm |
Phosalone (BioDeep_00000002277) Formula: C12H15ClNO4PS2 (366.9869) |
4.72 (100%) | Vitis vinifera [PO:0009085] exocarp |
| MSI_000055215 Unreliable | 367.981 | 367.981 ~ 367.981 MzDiff: none |
Not Annotated | 1.49 (0%) | MALDI - DHB [NOVOCELL:BACKGROUND] blank |
| MSI_000004376 Unreliable | 367.9811 | 367.9811 ~ 367.9811 MzDiff: none |
Not Annotated | 0.7 (0%) | Homo sapiens [UBERON:0002107] liver |
| MSI_000040690 Unreliable | 367.9781 | 367.9781 ~ 367.9781 MzDiff: none |
methyl 5,7-dichloro-3,8-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylate (BioDeep_00002231476) Formula: C16H10Cl2O6 (367.9854) |
2.26 (100%) | Posidonia oceanica [PO:0006036] root epidermis |
Found 7 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| m/z_367.9811 Formula: - (n/a) Adducts: (Ppm: 0) |
Homo sapiens (Liver) |
20171107_FIT4_DHBpos_p70_s50Resolution: 50μm, 70x70
|
|
| Phosalone Formula: C12H15ClNO4PS2 (366.9869) Adducts: [M+H]+ (Ppm: 15.1) |
Vitis vinifera (Fruit) |
grape_dhb_164_1Resolution: 17μm, 136x122
Grape berries fruit, condition: Late |
|
| Phosalone Formula: C12H15ClNO4PS2 (366.9869) Adducts: [M+H]+ (Ppm: 15.3) |
Vitis vinifera (Fruit) |
grape_dhb_163_1Resolution: 17μm, 132x115
Grape berries fruit, condition: Late |
|
| m/z_367.981 Formula: - (n/a) Adducts: (Ppm: 0) |
Mus musculus (Lung) |
image4Resolution: 40μm, 162x156
Fig 6c
Fig. 6 MALDI-MSI of U13C-PC16:0/16:0 acyl chain remodeling. A: Averaged MALDI mass spectrum from lung tissue collected from mice euthanized 12 h after administration of D9-choline and U13C-DPPC–containing Poractant alfa surfactant. The ion at m/z 828.6321 is assigned as the [M+Na]+ ion of 13C24-PC16:0_20:4 formed by acyl remodeling of U13C-PC16:0/16:0. The “NL” value refers to the intensity of the base peak in the full range MS1 spectrum. B: MS/MS spectrum of precursor ions at m/z 828.5 ± 0.5 with fragment ions originating from [13C24-PC16:0_20:4+Na]+ annotated. Part-per-million (ppm) mass errors are provided in parentheses. C, D: MALDI-MSI data of [U13C-DPPC+Na]+ (blue), [PC36:4+Na]+ (green) and [13C24-PC16:0_20:4+Na]+ (red) in lung tissue collected from mice (C) 12 h and (D) 18 h after label administration. All images were visualized using total-ion-current normalization and hotspot removal (high quantile = 99%). MS/MS, tandem mass spectrometry; MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC. |
|
| m/z_367.9811 Formula: - (n/a) Adducts: (Ppm: 0) |
Mus musculus (Lung) |
image5Resolution: 40μm, 163x183
Supplementary Figure S8. MALDI-MSI data of mouse lung tissue administered with D9-choline and
U 13C-DPPC–containing Poractant alfa surfactant (labels administered 18 h prior to sacrifice). Ion
images of (a) m/z 796.6856 ([U13C-DPPC+Na]+), (b) m/z 756.5154 [PC32:0+Na]+ and (c) m/z 765.6079
([D9-PC32:0+Na]+). (d) Overlay image of [U13C-DPPC+Na]+ (red) and [D9-PC32:0+Na]+ (green).
Parts per million (ppm) mass errors are indicated in parentheses. All images were visualised using totalion-current normalisation and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. |
|
| methyl 5,7-dichloro-3,8-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylate Formula: C16H10Cl2O6 (367.9854) Adducts: [M]+ (Ppm: 18.5) |
Posidonia oceanica (root) |
MS1_20180404_PO_1200Resolution: 17μm, 193x208
|
|
| cis-2,3-Dihydrodiol-DDE Formula: C14H10Cl4O2 (349.9435) Adducts: [M+NH4]+ (Ppm: 2.2) |
Mytilus edulis (gill) |
20190202_MS38_Crassostrea_Gill_350-1500_DHB_pos_A25_11um_305x210Resolution: 11μm, 305x210
single cell layer |
|
