M/Z: 352.144

Hit 1 annotations: Lomefloxacin_[M+H]+

在BioDeep NovoCell知识数据库中，参考离子总共被划分为4个级别。

Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。

Found 4 Reference Ions Near m/z 352.144

NovoCell ID	m/z	Mass Window	Metabolite	Ranking	Anatomy Context
MSI_000055061 Unreliable	352.144	352.144 ~ 352.144 MzDiff: `none`	Lomefloxacin (BioDeep_00000002814) Formula: C17H19F2N3O3 (351.1394)	1.55 (100%)	MALDI - DHB [NOVOCELL:BACKGROUND] blank
MSI_000032831 Unreliable	352.1498	352.1498 ~ 352.1498 MzDiff: `none`	alpha-Allocryptopine (BioDeep_00000000340) Formula: C21H23NO5 (369.1576)	0.16 (100%)	Posidonia oceanica [PO:0005020] vascular bundle
MSI_000033562 Unreliable	352.1498	352.1498 ~ 352.1498 MzDiff: `none`	alpha-Allocryptopine (BioDeep_00000000340) Formula: C21H23NO5 (369.1576)	1.66 (100%)	Posidonia oceanica [PO:0005352] xylem
MSI_000037292 Unreliable	352.15	352.15 ~ 352.15 MzDiff: `none`	alpha-Allocryptopine (BioDeep_00000000340) Formula: C21H23NO5 (369.1576)	1.95 (100%)	Posidonia oceanica [UBERON:0000329] hair root

Found 1 Sample Hits

Metabolite	Species	Sample
Lomefloxacin Formula: C17H19F2N3O3 (351.1394) Adducts: [M+H]+ (Ppm: 7.7)	Mus musculus (Lung)	image4 Resolution: 40μm, 162x156 Description Fig 6c Fig. 6 MALDI-MSI of U13C-PC16:0/16:0 acyl chain remodeling. A: Averaged MALDI mass spectrum from lung tissue collected from mice euthanized 12 h after administration of D9-choline and U13C-DPPC–containing Poractant alfa surfactant. The ion at m/z 828.6321 is assigned as the [M+Na]+ ion of 13C24-PC16:0_20:4 formed by acyl remodeling of U13C-PC16:0/16:0. The “NL” value refers to the intensity of the base peak in the full range MS1 spectrum. B: MS/MS spectrum of precursor ions at m/z 828.5 ± 0.5 with fragment ions originating from [13C24-PC16:0_20:4+Na]+ annotated. Part-per-million (ppm) mass errors are provided in parentheses. C, D: MALDI-MSI data of [U13C-DPPC+Na]+ (blue), [PC36:4+Na]+ (green) and [13C24-PC16:0_20:4+Na]+ (red) in lung tissue collected from mice (C) 12 h and (D) 18 h after label administration. All images were visualized using total-ion-current normalization and hotspot removal (high quantile = 99%). MS/MS, tandem mass spectrometry; MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC.

Metabolite

Species

Sample

Lomefloxacin

Formula: C17H19F2N3O3 (351.1394)
Adducts: [M+H]+ (Ppm: 7.7)

Mus musculus (Lung)

image4

Resolution: 40μm, 162x156

Description

Fig 6c Fig. 6 MALDI-MSI of U13C-PC16:0/16:0 acyl chain remodeling. A: Averaged MALDI mass spectrum from lung tissue collected from mice euthanized 12 h after administration of D9-choline and U13C-DPPC–containing Poractant alfa surfactant. The ion at m/z 828.6321 is assigned as the [M+Na]+ ion of 13C24-PC16:0_20:4 formed by acyl remodeling of U13C-PC16:0/16:0. The “NL” value refers to the intensity of the base peak in the full range MS1 spectrum. B: MS/MS spectrum of precursor ions at m/z 828.5 ± 0.5 with fragment ions originating from [13C24-PC16:0_20:4+Na]+ annotated. Part-per-million (ppm) mass errors are provided in parentheses. C, D: MALDI-MSI data of [U13C-DPPC+Na]+ (blue), [PC36:4+Na]+ (green) and [13C24-PC16:0_20:4+Na]+ (red) in lung tissue collected from mice (C) 12 h and (D) 18 h after label administration. All images were visualized using total-ion-current normalization and hotspot removal (high quantile = 99%). MS/MS, tandem mass spectrometry; MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC.