M/Z: 220.1545

Hit 2 annotations: Sebacic acid_[M+NH4]+; Diphenhydramine_[M+H-2H2O]+

在BioDeep NovoCell知识数据库中，参考离子总共被划分为4个级别。

Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。

Found 2 Reference Ions Near m/z 220.1545

NovoCell ID	m/z	Mass Window	Metabolite	Ranking	Anatomy Context
MSI_000052648 Reliable	220.1467	220.1463 ~ 220.1469 MzDiff: `2.8 ppm`	Diphenhydramine (BioDeep_00000001461) Formula: C17H21NO (255.1623)	39.22 (100%)	DESI [NOVOCELL:BACKGROUND] blank
MSI_000055741 Unreliable	220.1471	220.1471 ~ 220.1471 MzDiff: `none`	Diphenhydramine (BioDeep_00000001461) Formula: C17H21NO (255.1623)	0.4 (100%)	Homo sapiens [UBERON:0007779] transudate

Found 2 Sample Hits

Metabolite Species Sample

Metabolite	Species	Sample
Sebacic acid Formula: C10H18O4 (202.1205) Adducts: [M+NH4]+ (Ppm: 0.8)	Marker Pen (NA)	3ul_0.8Mpa_RAW_20241016-PAPER PNMK Resolution: 30μm, 315x42 Description By writing the four English letters “PNMK” on white paper with a marker pen, and then scanning with a DESI ion source to obtain the scanning result. The signal of the chemical substances on the marker pen used appears on the channel with an m/z value of `322.1918`, `323.1953`, `546.4010`, and etc, from the single cell deconvolution sampling layer `class_4`. This test data was tested by chuxiaoping from PANOMIX’s R&D laboratory.
Diphenhydramine Formula: C17H21NO (255.1623) Adducts: [M+H-2H2O]+ (Ppm: 7.5)	Homo sapiens (colorectal adenocarcinoma)	439TopL, 409TopR, 429BottomL, 419BottomR-profile Resolution: 17μm, 157x136 Description The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

Sebacic acid

Formula: C10H18O4 (202.1205)
Adducts: [M+NH4]+ (Ppm: 0.8)

Marker Pen (NA)

3ul_0.8Mpa_RAW_20241016-PAPER PNMK

Resolution: 30μm, 315x42

Description

By writing the four English letters “PNMK” on white paper with a marker pen, and then scanning with a DESI ion source to obtain the scanning result. The signal of the chemical substances on the marker pen used appears on the channel with an m/z value of 322.1918, 323.1953, 546.4010, and etc, from the single cell deconvolution sampling layer class_4. This test data was tested by chuxiaoping from PANOMIX’s R&D laboratory.

Diphenhydramine

Formula: C17H21NO (255.1623)
Adducts: [M+H-2H2O]+ (Ppm: 7.5)

Homo sapiens (colorectal adenocarcinoma)

439TopL, 409TopR, 429BottomL, 419BottomR-profile

Resolution: 17μm, 157x136

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).