MSI_000065828

Unreliable

排名分数: 2.69
参考来源: Homo sapiens (UBERON:0007779: transudate)

M/z: 272.9998
Mass Window: 272.9997 ~ 272.9999 (1.0 ppm)

参考注释

Zoledronate_[M+H]+ (BioDeep_00000033228)
[1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid

Formula: C5H10N2O7P2 (271.996325)
SMILES: C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O

Zoledronate (zoledronic acid, marketed by Novartis under the trade names Zometa and Reclast) is a bisphosphonate. Zometa is used to prevent skeletal fractures in patients with cancers such as multiple myeloma and prostate cancer. It can also be used to treat hypercalcemia of malignancy and can be helpful for treating pain from bone metastases. An annual dose of Zoledronate may also prevent recurring fractures in patients with a previous hip fracture. Zoledronate is a single 5 mg infusion for the treatment of Pagets disease of bone. In 2007, the FDA also approved Reclast for the treatment of postmenopausal osteoporosis. M - Musculo-skeletal system > M05 - Drugs for treatment of bone diseases > M05B - Drugs affecting bone structure and mineralization > M05BA - Bisphosphonates D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates