MSI_000065640

Unreliable

排名分数: 2.27
参考来源: Homo sapiens (UBERON:0001155: colon)

M/z: 281.0358
Mass Window: 281.0358 ~ 281.0359 (0.2 ppm)

参考注释

N-[(1-Chloro-4-hydroxyisoquinolin-3-YL)carbonyl]glycine_[M+H]+ (BioDeep_00000179042)
2-{[(1-chloro-4-hydroxyisoquinolin-3-yl)(hydroxy)methylidene]amino}acetate

Formula: C12H9ClN2O4 (280.0250824)
SMILES: C1=CC=C2C(=C1)C(=C(N=C2Cl)C(=O)NCC(=O)O)O

FG-2216 (IOX3) is a potent and orally active inhibitor of HIF prolyl hydroxylase-2 (PHD2), with an IC50 of 3.9 μM. FG-2216 induces robust erythropoietin and modest fetal hemoglobin in vivo[1][2][3].