MSI_000065414

Unreliable

排名分数: 1.71
参考来源: Homo sapiens (UBERON:0001155: colon)

M/z: 508.4729
Mass Window: 508.4729 ~ 508.4729 (none)

参考注释

FAHFA(16:1(9Z)/5-O-16:0)_[M]+ (BioDeep_00000104531)
5-[(9Z)-hexadec-9-enoyloxy]hexadecanoic acid

Formula: C32H60O4 (508.449136)
SMILES: [H]\C(CCCCCC)=C(/[H])CCCCCCCC(=O)OC(CCCCCCCCCCC)CCCC(O)=O

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are endogenous lipids found in adipose tissue and serum that correlate with insulin sensitivity and are reduced in insulin-resistant humans. Structurally, they are characterized by a branched ester linkage between a fatty acid and a hydroxy-fatty acid. Different positions of the branched ester on the hydroxy fatty acid results in different isomers. FAHFA(16:1(9Z)/5-O-16:0), in particular, is formed from the condensation of the carboxy group of palmitoleic acid with the hydroxy group of 5-hydroxyhexadecanoic acid. It is alternatively named 5-POHPA since it is the 5-hydroxy isomer of the POHPA (palmitoleic acid-hydroxypalmitic acid) family.