MSI_000062288

Unavailable

排名分数: -0.35
参考来源: Mus musculus (UBERON:0001950: neocortex)

M/z: 256.1761
Mass Window: 256.1761 ~ 256.1761 (none)

参考注释

Tripelennamine_[M+H]+ (BioDeep_00000002300)
N-benzyl-N-[2-(dimethylamino)ethyl]pyridin-2-amine

Formula: C16H21N3 (255.1735386)
SMILES: CN(C)CCN(CC1=CC=CC=C1)C1=CC=CC=N1

Tripelennamine is only found in individuals that have used or taken this drug. It is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically. [PubChem]Tripelennamine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AC - Substituted ethylene diamines D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist D018926 - Anti-Allergic Agents