MSI_000057969

Reliable

排名分数: 3.71
参考来源: DESI (NOVOCELL:BACKGROUND: blank)

M/z: 329.2336
Mass Window: 329.2333 ~ 329.2339 (2.4 ppm)

参考注释

Trimethoprim_[M+K]+ (BioDeep_00000001590)
5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine

Formula: C14H18N4O3 (290.1378838)
SMILES: COc1cc(Cc2c[nH]c(=N)[nH]c2=N)cc(OC)c1OC

A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by sulfonamides and the trimethoprim-sulfamethoxazole combination is the form most often used. It is sometimes used alone as an antimalarial. Trimethoprim resistance has been reported. [PubChem] Trimethoprim. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=738-70-5 (retrieved 2024-07-09) (CAS RN: 738-70-5). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).