MSI_000057757

Reliable

排名分数: 7
参考来源: DESI (NOVOCELL:BACKGROUND: blank)

M/z: 287.1866
Mass Window: 287.1863 ~ 287.1867 (1.6 ppm)

参考注释

Thonzylamine_[M+H]+ (BioDeep_00000169699)
N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine

Formula: C16H22N4O (286.1793522)
SMILES: CN(C)CCN(CC1=CC=C(C=C1)OC)C2=NC=CC=N2

D - Dermatologicals > D04 - Antipruritics, incl. antihistamines, anesthetics, etc. > D04A - Antipruritics, incl. antihistamines, anesthetics, etc. > D04AA - Antihistamines for topical use R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AC - Antiallergic agents, excl. corticosteroids R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use > R06AC - Substituted ethylene diamines D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist Thonzylamine is a first-generation ethylenediamine H1-antihistamine. Thonzylamine is an orally active H1 histamine receptor antagonist, exhibits good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases[1][2].