MSI_000057329

Unreliable

排名分数: 1.14
参考来源: Homo sapiens (UBERON:0007779: transudate)

M/z: 245.1289
Mass Window: 245.1289 ~ 245.1289 (none)

参考注释

Etomidate_[M+H]+ (BioDeep_00000001469)
(R)-(+)-1-(alpha-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester

Formula: C14H16N2O2 (244.1211716)
SMILES: CCOC(=O)C1=CN=CN1[C@H](C)C1=CC=CC=C1

Etomidate is only found in individuals that have used or taken this drug. It is an midazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic. [PubChem]Etomidate binds at a distinct binding site associated with a Cl^- ionopore at the GABA_A receptor, increasing the duration of time for which the Cl^- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics N - Nervous system > N01 - Anesthetics > N01A - Anesthetics, general C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent