MSI_000057306

Unreliable

排名分数: 1.16
参考来源: Homo sapiens (UBERON:0007779: transudate)

M/z: 264.1347
Mass Window: 264.1347 ~ 264.1347 (none)

参考注释

Gamma-CEHC_[M]+ (BioDeep_00000018948)
3-(6-hydroxy-2,7,8-trimethyl-3,4-dihydro-2H-1-benzopyran-2-yl)propanoic acid

Formula: C15H20O4 (264.136152)
SMILES: CC1=C(C=C2CCC(OC2=C1C)(C)CCC(=O)O)O

gamma-CEHC (gamma-carboxyethyl hydroxychroman) is a metabolite of vitamin E. Smokers have a significantly higher excretion level of urinary gamma-CEHC, and therefore require more vitamin E compared to non-smokers. Cigarette smoking is associated with increased oxidative stress and increased risk of degenerative disease. As the major lipophilic antioxidant, requirements for vitamin E may also be higher in smokers due to increased utilization (PMID: 15493460). gamma-CEHC is metabolites of Vitamin E.