MSI_000057114
Unreliable
排名分数: 1.38
参考来源: Homo sapiens (UBERON:0007779: transudate)
M/z: 280.2023
Mass Window: 280.2023 ~ 280.2023 (none)
参考注释
12-HHTrE_[M]+ (BioDeep_00000004028)12(S)-Hydroxy-(5Z,8Z,10E)-heptadeca-5,8,10-trienoic acid anion
Formula: C17H28O3 (280.2038338)
SMILES:
CCCCC[C@H](O)\C=C\C=C\C\C=C/CCCC(O)=O
12(S)-HHTrE is an unusual product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of the human platelet.1 It is biosynthesized by thromboxane (TX) synthesis from prostaglandin H2 (PGH2) concurrently with TXA2. The biological role of 12(S)-HHTrE is uncertain. It is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH. [HMDB] 12(S)-HHTrE is an unusual product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of the human platelet.1 It is biosynthesized by thromboxane (TX) synthesis from prostaglandin H2 (PGH2) concurrently with TXA2. The biological role of 12(S)-HHTrE is uncertain. It is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.
