MSI_000056953

Unreliable

排名分数: 1.55
参考来源: Homo sapiens (UBERON:0007779: transudate)

M/z: 451.2744
Mass Window: 451.2744 ~ 451.2744 (none)

参考注释

Cinalukast_[M+K]+ (BioDeep_00000033249)
3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid

Formula: C23H28N2O3S (412.18205380000006)
SMILES: CCC(CC)(CC(=O)NC1=CC=CC(\C=C\C2=NC(=CS2)C2CCC2)=C1)C(O)=O

Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent