MSI_000056548

Reliable

排名分数: 4.76
参考来源: DESI (NOVOCELL:BACKGROUND: blank)

M/z: 326.3258
Mass Window: 326.3257 ~ 326.3259 (0.8 ppm)

参考注释

Procyclidine_[M+K]+ (BioDeep_00000002061)
1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol

Formula: C19H29NO (287.2249024)
SMILES: C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O

Procyclidine is only found in individuals that have used or taken this drug. It is a muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism. [PubChem]The mechanism of action is unknown. It is thought that Procyclidine acts by blocking central cholinergic receptors, and thus balancing cholinergic and dopaminergic activity in the basal ganglia. Many of its effects are due to its pharmacologic similarities with atropine. Procyclidine exerts an antispasmodic effect on smooth muscle, and may produce mydriasis and reduction in salivation. D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents N - Nervous system > N04 - Anti-parkinson drugs > N04A - Anticholinergic agents > N04AA - Tertiary amines C78272 - Agent Affecting Nervous System > C66880 - Anticholinergic Agent > C29704 - Antimuscarinic Agent D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D018680 - Cholinergic Antagonists