MSI_000055895

Unavailable

排名分数: -0.31
参考来源: Homo sapiens (UBERON:0007779: transudate)

M/z: 293.1798
Mass Window: 293.1798 ~ 293.1798 (none)

参考注释

Thioperamide_[M+H]+ (BioDeep_00000011972)
N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carboimidothioic acid

Formula: C15H24N4S (292.1721584)
SMILES: C1CCC(CC1)NC(=S)N2CCC(CC2)C3=CN=CN3

D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists D002491 - Central Nervous System Agents > D000927 - Anticonvulsants Thioperamide (MR-12842) is a potent, orally available, brain penetrant and selective H3 receptor antagonist with a Ki of 4.3 nM for inhibition of [3H]histamine release. Thioperamide inhibits [3H]histamine synthesis with a Ki of 31 nM[1].