MSI_000055868

Unavailable

排名分数: -0.23
参考来源: Homo sapiens (UBERON:0007779: transudate)

M/z: 381.2326
Mass Window: 381.2326 ~ 381.2326 (none)


参考注释
Forasartan_[M+H-2H2O]+ (BioDeep_00000033321)
5-[(dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]pyridine

Formula: C23H28N8 (416.2436808)
SMILES: CCCCC1=NN(C(=N1)CCCC)CC2=CN=C(C=C2)C3=CC=CC=C3C4=NNN=N4


Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension. Forasartan competes with angiotensin II for binding at the AT1 receptor subtype. As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance. C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C66930 - Angiotensin II Receptor Antagonist