MSI_000055768

Unreliable

排名分数: 0.28
参考来源: Homo sapiens (UBERON:0007779: transudate)

M/z: 179.0355
Mass Window: 179.0355 ~ 179.0355 (none)

参考注释

2,3-Dihydroxy-5-methylthio-4-pentenoic acid_[M+H]+ (BioDeep_00000169780)
(2R,3R,4E)-2,3-Dihydroxy-5-(methylsulphanyl)pent-4-enoic acid

Formula: C6H10O4S (178.029978)
SMILES: CS\C=C\[C@@H](O)[C@@H](O)C(O)=O

2,3-Dihydroxy-5-methylthio-4-pentenoic acid (DMTPA) is a hydroxy fatty acid with a thioenolether group. DMTPA was previously an unknown potential plasma biomarker for glomerular filtration rate (GFR) but its structure has since been elucidated (PMID: 29578721). DMTPA is possibly involved in the methionine salvage pathway (MSP) and may potentially be synthesized from methylthioadenosine (MTA). MTA is a byproduct of S-adenosylmethionine (SAM) during polyamine biosynthesis.