MSI_000055708

Reliable

排名分数: 2.54
参考来源: Homo sapiens (UBERON:0007779: transudate)

M/z: 236.1054
Mass Window: 236.1052 ~ 236.1059 (2.9 ppm)

参考注释

Proguanil_[M+H-H2O]+ (BioDeep_00000002125)
(E)-1-({amino[(4-chlorophenyl)amino]methylidene}amino)-N-(propan-2-yl)methenimidamide

Formula: C11H16ClN5 (253.10941659999997)
SMILES: CC(C)\N=C(/N)N=C(N)NC1=CC=C(Cl)C=C1

Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite. P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01B - Antimalarials > P01BB - Biguanides D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent C471 - Enzyme Inhibitor > C2153 - Dihydrofolate Reductase Inhibitor D007004 - Hypoglycemic Agents > D001645 - Biguanides D009676 - Noxae > D000963 - Antimetabolites