MSI_000053971

Unreliable

排名分数: 3.2
参考来源: MALDI - CHCA (NOVOCELL:BACKGROUND: blank)

M/z: 333.0578
Mass Window: 333.0578 ~ 333.0578 (0.1 ppm)

参考注释

Laricitrin_[M+H]+ (BioDeep_00000003235)
2-(3,4-Dihydroxy-5-methoxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one

Formula: C16H12O8 (332.0532152)
SMILES: C1(O)=CC2OC(C3C=C(OC)C(O)=C(O)C=3)=C(O)C(=O)C=2C(O)=C1

Laricitrin, also known as 3-O-methylmyricetin or 3,4,5,5,7-pentahydroxy-3-methoxyflavone, belongs to the class of organic compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. Thus, laricitrin is considered to be a flavonoid lipid molecule. Laricitrin is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. BioTransformer predicts that laricitrin is a product of isorhamnetin metabolism via a hydroxylation-of-benzene-ortho-to-edg reaction catalyzed by the CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes (PMID: 30612223).