MSI_000053132

Unreliable

排名分数: 2.93
参考来源: DESI (NOVOCELL:BACKGROUND: blank)

M/z: 340.2014
Mass Window: 340.2014 ~ 340.2014 (none)

参考注释

Methylergonovine_[M+H]+ (BioDeep_00000018257)
(4R,7R)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide

Formula: C20H25N3O2 (339.194667)
SMILES: [H][C@@]12CC3=CNC4=CC=CC(=C34)C1=C[C@H](CN2C)C(=O)N[C@@H](CC)CO

Methylergonovine is only found in individuals that have used or taken this drug. It is a homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)Methylergonovine acts directly on the smooth muscle of the uterus and increases the tone, rate, and amplitude of rhythmic contractions through binding and the resultant antagonism of the dopamine D1 receptor. Thus, it induces a rapid and sustained tetanic uterotonic effect which shortens the third stage of labor and reduces blood loss. G - Genito urinary system and sex hormones > G02 - Other gynecologicals > G02A - Uterotonics > G02AB - Ergot alkaloids C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant D012102 - Reproductive Control Agents > D010120 - Oxytocics