MSI_000052668

Reliable

排名分数: 16.17
参考来源: DESI (NOVOCELL:BACKGROUND: blank)

M/z: 341.1963
Mass Window: 341.196 ~ 341.1966 (2.3 ppm)

参考注释

Pentamidine_[M+H]+ (BioDeep_00000002280)
American pharmaceutical partners brand 1 OF pentamidine isethionate

Formula: C19H24N4O2 (340.18991639999996)
SMILES: C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N

Pentamidine is only found in individuals that have used or taken this drug. It is an antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects. [PubChem]The mode of action of pentamidine is not fully understood. It is thought that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids, and proteins. D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent D000890 - Anti-Infective Agents > D000935 - Antifungal Agents C254 - Anti-Infective Agent > C514 - Antifungal Agent