MSI_000051432
Unreliable
排名分数: 0
参考来源: Mytilus edulis (UBERON:2001856: gill ray)
M/z: 506.2644
Mass Window: 506.2644 ~ 506.2644 (none)
参考注释
Calcimycin_[M+H-H2O]+ (BioDeep_00000008595)4-CHLORO-2-NITROBENZYLALCOHOL
Formula: C29H37N3O6 (523.2682222000001)
SMILES:
CC1CCC2(C(CC(C(O2)C(C)C(=O)C3=CC=CN3)C)C)OC1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D007476 - Ionophores > D061207 - Calcium Ionophores D049990 - Membrane Transport Modulators C254 - Anti-Infective Agent > C258 - Antibiotic Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis[1][2][3][4].