MSI_000051123

Unreliable

排名分数:
参考来源: Mytilus edulis (UBERON:2001856: gill ray)

M/z: 362.1438
Mass Window: 362.1438 ~ 362.1438 (none)

参考注释

Bisacodyl_[M+H]+ (BioDeep_00000176734)
4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetic acid

Formula: C22H19NO4 (361.1314014000001)
SMILES: CC(=O)OC1=CC=C(C=C1)C(C1=CC=C(OC(C)=O)C=C1)C1=CC=CC=N1

A - Alimentary tract and metabolism > A06 - Drugs for constipation > A06A - Drugs for constipation > A06AB - Contact laxatives A - Alimentary tract and metabolism > A06 - Drugs for constipation > A06A - Drugs for constipation > A06AG - Enemas C78276 - Agent Affecting Digestive System or Metabolism > C29697 - Laxative D005765 - Gastrointestinal Agents > D002400 - Cathartics D005765 - Gastrointestinal Agents > D054368 - Laxatives Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect[1].