MSI_000046748

Reliable

排名分数: 3.54
参考来源: Mus musculus (UBERON:0002107: liver)

M/z: 399.0899
Mass Window: 399.0899 ~ 399.0899 (none)

参考注释

dehydrofelodipine_[M+NH4]+ (BioDeep_00000054434)
3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate

Formula: C18H17Cl2NO4 (381.0534582000001)
SMILES: CCOC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl

dehydrofelodipine is a metabolite of felodipine. Felodipine is a calcium channel blocker (calcium antagonist), a drug used to control hypertension (high blood pressure). It is marketed under the brand name Plendil by AstraZeneca and Renedil by Sanofi-Aventis. The formulation patent for the substance expired in 2007. AstraZeneca dropped Plendil from its support and AZ&Me free Rx access program in October 2008. (Wikipedia)