MSI_000044622

Unavailable

排名分数: -0.39
参考来源: Rattus norvegicus (UBERON:0002264: olfactory bulb)

M/z: 643.1157
Mass Window: 643.1157 ~ 643.1157 (none)

参考注释

Afoxolaner_[M+NH4]+ (BioDeep_00000175774)
2-[(4-{5-[3-chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl}naphthalen-1-yl)formamido]-N-(2,2,2-trifluoroethyl)ethanimidic acid

Formula: C26H17ClF9N3O3 (625.081467)
SMILES: C1C(=NOC1(C2=CC(=CC(=C2)Cl)C(F)(F)F)C(F)(F)F)C3=CC=C(C4=CC=CC=C43)C(=O)NCC(=O)NCC(F)(F)F

C254 - Anti-Infective Agent > C276 - Antiparasitic Agent Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod[1][2].