MSI_000043440

Reliable

排名分数: 5.6
参考来源: Homo sapiens (UBERON:0001043: esophagus)

M/z: 201.0381
Mass Window: 201.038 ~ 201.0381 (0.4 ppm)

参考注释

Maleylacetoacetic acid_[M+H]+ (BioDeep_00000004547)
(2Z)-4,6-Dioxo-2-octenedioic acid

Formula: C8H8O6 (200.0320868)
SMILES: C(=O)(O)/C=C\C(=O)CC(=O)CC(=O)O

Maleylacetoacetic acid, also known as 4-maleylacetoacetate, is an intermediate in the metabolism of tyrosine. Homogentisate 1,2-dioxygenase (HGD) is the enzyme which catalyzes the conversion of homogentisate into 4-maleylacetoacetate. HGD is involved in the catabolism of aromatic rings, more specifically in the breakdown of the amino acids tyrosine and phenylalanine.