MSI_000027309

Unreliable

排名分数: 2.03
参考来源: Mus musculus (UBERON:0000913: interstitial fluid)

M/z: 639.9942
Mass Window: 639.9942 ~ 639.9942 (none)

参考注释

N-desethylamiodarone_[M+Na]+ (BioDeep_00000027048)
{2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}(ethyl)amine

Formula: C23H25I2NO3 (616.9923879999999)
SMILES: CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCNCC)I

N-Desethylamiodarone is a CYP3A4 metabolite of amiodarone. Amiodarone is recognized as an effective drug in the treatment of arrhythmias. The main in-vivo metabolite of amiodarone, N-desethylamiodarone (DEAM), possesses clinically relevant class-II antiarrhythmic and vasodilator activities. (PMID: 11138840)