MSI_000026233

Unreliable

排名分数: 1.8
参考来源: Mus musculus (UBERON:0000913: interstitial fluid)

M/z: 641.0322
Mass Window: 641.0322 ~ 641.0322 (none)

参考注释

Pentosan Polysulfate_[M+K]+ (BioDeep_00000033254)
[(2R,3R,4S,5R)-2-Hydroxy-5-{[(2S,3R,4S,5R)-5-hydroxy-3,4-bis(sulphooxy)oxan-2-yl]oxy}-4-(sulphooxy)oxan-3-yl]oxidanesulphonic acid

Formula: C10H18O21S4 (601.9223458)
SMILES: O[C@@H]1CO[C@@H](O[C@@H]2CO[C@@H](O)[C@H](OS(O)(=O)=O)[C@H]2OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H]1OS(O)(=O)=O

Pentosan Polysulfate is only found in individuals that have used or taken this drug. It is a sulfated pentosyl polysaccharide with heparin-like properties. [PubChem]Pentosan polysulfate is a polymer of xylose hydrogen sulfate and contains two sulfate groups per carbohydrate monomer. It binds Fibroblast growth factors (FGFs) as well as other heparin-binding growth factors. It has been shown to interact also with the heparin-binding site of FGFR-1. It inhibits the growth of SW13 adrenocortical cells transfected with FGF-4 and tumorigenicity of MCF-7 breast carcinoma cells transfected with FGF-1 or FGF-4. Cartrophen-Vet is a 100mg/ml formulation of Pentosan polysulphate that has been used in Australia since the early 1990s. It is produced by Biopharm Australia , a subsidiary of R-Biopharm, Germany.; Pentosan polysulfate sodium is a low molecular weight heparin-like compound. It has anticoagulant and fibrinolytic effects. Pentosan polysulfate is found in garden onion, fig, and tamarind. C78275 - Agent Affecting Blood or Body Fluid > C263 - Anticoagulant Agent D006401 - Hematologic Agents > D000925 - Anticoagulants