MSI_000021330

Unreliable

排名分数: 1.09
参考来源: Mus musculus (UBERON:0001499: muscle of arm)

M/z: 685.4255
Mass Window: 685.4255 ~ 685.4255 (none)

参考注释

Gluten exorphin C_[M+NH4]+ (BioDeep_00000053857)
[(2S)-1-{[(1,1-dihydroxy-4-methylpentan-2-yl)amino]oxy}-3-hydroxy-1-oxopropan-2-yl]amino (2S,3S)-2-[({1-[2-amino-1-hydroxy-3-(4-hydroxycyclohexyl)propoxy]pyrrolidin-2-yl}(hydroxy)methoxy)amino]-3-methylpentanoate

Formula: C29H57N5O12 (667.4003522)
SMILES:

[H][C@](C)(CC)[C@]([H])(NOC([H])(O)C1([H])CCCN1OC([H])(O)C([H])(N)CC1([H])CCC([H])(O)CC1)C(=O)ON[C@@]([H])(CO)C(=O)ONC([H])(CC(C)C)C(O)O

Gluten exorphin B5 is a pentapeptide with the sequence Tyr-Pro-Ile-Ser-Leu. Gluten exorphins are a group of opioid peptides which are formed during digestion of the gluten protein. It has been hypothesized that people with autism and schizophrenia have abnormal leakage from the gut of these compounds, which then pass into the brain and disrupt brain function. This is partly the basis for the gluten-free, casein-free diet. The scientific evidence for this diet and its effects is still disputed.