MSI_000015175

Unavailable

排名分数: -0.6
参考来源: Plant (PO:0006036: root epidermis)

M/z: 246.0503
Mass Window: 246.0503 ~ 246.0503 (none)

参考注释

Busulfan_[M]+ (BioDeep_00000006359)
4-(methanesulfonyloxy)butyl methanesulfonate

Formula: C6H14O6S2 (246.0231784)
SMILES: CS(=O)(=O)OCCCCOS(=O)(=O)C

An alkylating agent having a selective immunosuppressive effect on bone marrow. It has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen. [PubChem] L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AB - Alkyl sulfonates C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D000970 - Antineoplastic Agents > D019653 - Myeloablative Agonists D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D009676 - Noxae > D000477 - Alkylating Agents