MSI_000013270

Unavailable

排名分数: -0.91
参考来源: Plant (PO:0005020: vascular bundle)

M/z: 542.9914
Mass Window: 542.9914 ~ 542.9914 (none)

参考注释

2-Chloro-2'-deoxyadenosine-5'-triphosphate_[M+NH4]+ (BioDeep_00000054205)
({[({[(2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid

Formula: C10H15ClN5O12P3 (524.961861)
SMILES: NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O3)C2=NC(Cl)=N1

2-Chloro-2-deoxyadenosine-5-triphosphate is a metabolite of cladribine. Cladribine (trade names Litak and Movectro) is a drug used to treat hairy cell leukemia (HCL, leukemic reticuloendotheliosis) and multiple sclerosis. Its chemical name is 2-chlorodeoxyadenosine (2CDA). As a purine analog, it is a synthetic anti-cancer agent that also suppresses the immune system. Chemically, it mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, which interferes with the cells ability to process DNA. (Wikipedia)