MSI_000011247

Unreliable

排名分数: 1.66
参考来源: Mus musculus (UBERON:0012378: muscle layer of urinary bladder)

M/z: 423.9902
Mass Window: 423.9902 ~ 423.9902 (none)

参考注释

Thioguanosine 5'-diphosphate_[M+H-2H2O]+ (BioDeep_00000054335)
[({[(2R,3S,4R,5R)-5-(2-amino-6-sulfanylidene-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid

Formula: C10H15N5O10P2S (459.00148700000005)
SMILES: NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=S)N1

Thioguanosine 5-diphosphate is a metabolite of azathioprine. Azathioprine is a purine analogue immunosuppressive drug. It is used to prevent rejection following organ transplantation, and to treat a vast array of autoimmune diseases, including rheumatoid arthritis, pemphigus, inflammatory bowel disease, multiple sclerosis, autoimmune hepatitis, atopic dermatitis, myasthenia gravis, neuromyelitis optica or Devics disease, restrictive lung disease, and others (Wikipedia).