MSI_000011207

Unreliable

排名分数: 1.78
参考来源: Mus musculus (UBERON:0012378: muscle layer of urinary bladder)

M/z: 444.1053
Mass Window: 444.1053 ~ 444.1053 (none)

参考注释

N-debutylhalofantrine_[M+H]+ (BioDeep_00000054436)
3-(butylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol

Formula: C22H22Cl2F3NO (443.1030458)
SMILES: CCCCNCCC(C1=C2C=CC(=CC2=C3C=C(C=C(C3=C1)Cl)Cl)C(F)(F)F)O

N-debutylhalofantrine is a metabolite of halofantrine. Halofantrine is a drug used to treat malaria. Halofantrines structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown. A crystallographic study have shown that halofantrine binds to hematin in vitro, suggesting a possible mechanism of action. (Wikipedia) D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents