MSI_000007576

排名分数: 1.69
参考来源: Rattus norvegicus (UBERON:0004359: corpus epididymis)

M/z: 461.3811
Mass Window: 461.381 ~ 461.3812 (0.6 ppm)

参考注释

Perifosine_[M]+ (BioDeep_00000182272)
1,1-dimethyl-4-{[(octadecyloxy)phosphinato]oxy}piperidin-1-ium

Formula: C25H52NO4P (461.36337620000006)
SMILES: CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1

C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C2188 - Alkylphosphocholine Compound C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C61074 - Serine/Threonine Kinase Inhibitor C274 - Antineoplastic Agent > C2122 - Cell Differentiating Agent > C1934 - Differentiation Inducer Perifosine is an oral Akt inhibitor which inhibits proliferation of different tumor cell lines with IC50s of 0.6-8.9 μM.