MSI_000003993

Unreliable

排名分数: 1.2
参考来源: Homo sapiens (UBERON:0002107: liver)

M/z: 247.0604
Mass Window: 247.0604 ~ 247.0604 (none)


参考注释
Sulfamerazine_[M+H-H2O]+ (BioDeep_00000018010)
4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide

Formula: C11H12N4O2S (264.0680932)
SMILES: CC1=NC(=NC=C1)NS(=O)(=O)C2=CC=C(C=C2)N


Sulfamerazine is only found in individuals that have used or taken this drug.It is a sulfanilamide that is used as an antibacterial agent. [PubChem]Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA. D - Dermatologicals > D06 - Antibiotics and chemotherapeutics for dermatological use > D06B - Chemotherapeutics for topical use > D06BA - Sulfonamides J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01ED - Long-acting sulfonamides C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D000890 - Anti-Infective Agents > D013424 - Sulfanilamides